PIMA533115

ATF2 Recombinant Rabbit Monoclonal Antibody (3D12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533115-Each-of-1 In Stock ₹ 50,596.50

PIMA533115 - Each of 1

₹ 50,596.50

In Stock

Quantity

1

Base Price: ₹ 50,596.50

GST (18%): ₹ 9,107.37

Total Price: ₹ 59,703.87

Antigen

ATF2

Classification

Recombinant Monoclonal

Concentration

0.61 mg/mL

Formulation

PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P15336, P16951, Q00969

Gene Symbols

Atf2

Immunogen

A synthesized peptide derived from human ATF2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

3D12

Conjugate

Unconjugated

Gene

Atf2

Gene Alias

Activating 2, Activating transcription factor 2, activating transcription factor 2 splice variant ATF2-var2, ATF2, Atf-2, cAMP response element-binding protein CRE-BP1, cAMP responsive element binding protein 2, formerly, cAMP-dependent transcription factor ATF-2, CREB2, CREB-2, CRE-BP, CREBP1, CRE-BP1, Cyclic AMP-dependent transcription factor ATF-2, cyclic AMP-responsive element-binding protein 2, D130078H02Rik, D18875, HB16, Histone acetyltransferase ATF2, MGC111558, mXBP, MXBP protein, OTTHUMP00000205345, OTTHUMP00000205347, OTTHUMP00000205348, OTTHUMP00000205350, OTTHUMP00000205352, OTTHUMP00000205353, OTTHUMP00000205354, Tg(Gzma-Klra1)7Wum, TREB7

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11909, 1386, 81647

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins
  • ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways
  • Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2
  • Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71
  • Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.