Bax Recombinant Rabbit Monoclonal Antibody (SZ3-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532031-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532031 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Bax
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q07812, Q07813, Q63690
Gene Symbols
BAX
Immunogen
Synthetic peptide within Human Bax aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
SZ3-07
Conjugate
Unconjugated
Gene
BAX
Gene Alias
apoptosis regulator BAX, Apoptosis regulator Bcl-X, Bax, Bax zeta, BAX-ALPHA, Bax-alpha protein, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, BCL2 associated X protein, BCL2 associated X, apoptosis regulator, BCL2 like 1, BCL2-associated protein, Bcl-2-associated protein Bax, Bcl2-associated protein Bax, Bcl-2-associated X protein, BCL2-associated X protein, BCL2-associated X protein omega, BCL2L, BCL2L1, Bcl2-L-1, BCL2L4, Bcl2-L-4, BCL2-like 1, bcl-2-like protein 1, Bcl-2-like protein 4, BCLX, Bcl-X, BCL-XL/S, PPP1R52, protein phosphatase 1, regulatory subunit 52
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12028, 24887, 581
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis
- Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function
- Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2
- The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain
- Bcl-2 is also expressed in different Isoforms
- Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha
- Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa)
- BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis
- Overexpression of BAX functions to promote cell death
- BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.