BAK Recombinant Rabbit Monoclonal Antibody (SU32-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532111-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532111 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
BAK
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q16611
Gene Symbols
BAK1
Immunogen
Synthetic peptide within Human Bak aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SU32-07
Conjugate
Unconjugated
Gene
BAK1
Gene Alias
Apoptosis regulator BAK, BAK, Bak1, BAK-LIKE, BCL2 antagonist/killer 1, Bcl2 homologous antagonist/killer, Bcl-2 homologous antagonist/killer, BCL2-antagonist/killer 1, BCL2L7, bcl2-L-7, BCL2-like 7 protein, BCL2-like 7protein, bcl-2-like protein 7, Bcl-2-likeous antagonist/killer, CDN1, MGC117255, MGC3887, N-Bak, N-BAK1, pro-apoptotic protein BAK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
578
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The protein encoded by this gene belongs to the BCL2 protein family
- BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities
- This protein localizes to mitochondria, and functions to induce apoptosis
- It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c
- This protein also interacts with the tumor suppressor P53 after exposure to cell stress.