DNMT3B Recombinant Rabbit Monoclonal Antibody (SY09-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532058-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532058 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
DNMT3B
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O88509, Q9UBC3
Gene Symbols
Dnmt3b
Immunogen
Synthetic peptide within Human Dnmt3b aa 61-110
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
SY09-07
Conjugate
Unconjugated
Gene
Dnmt3b
Gene Alias
DNA (cytosine-5-)-methyltransferase 3 beta, DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase 3 beta, DNA methyltransferase 3B, DNA methyltransferase HsaIIIB, DNA methyltransferase MmuIIIB, DNA MTase HsaIIIB, DNA MTase MmuIIIB, Dnmt3, DNMT3B, ICF, ICF1, M.HsaIIIB, m.MmuIIIB, MGC1090, MmuIIIB
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
13436, 1789, 444985
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation
- Studies in mice have demonstrated that DNA methylation is required for mammalian development
- This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation
- The protein localizes primarily to the nucleus and its expression is developmentally regulated
- Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome
- Six alternatively spliced transcript variants have been described
- The full length sequences of variants 4 and 5 have not been determined.