FNTB Recombinant Rabbit Monoclonal Antibody (SC06-44), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532260-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532260 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
FNTB
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P49356, Q02293
Gene Symbols
FNTB
Immunogen
Recombinant protein within Human FNTB aa 1-98
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
SC06-44
Conjugate
Unconjugated
Gene
FNTB
Gene Alias
2010013E13Rik, AA409500, CAAX farnesyltransferase subunit beta, EC 2.5.1.58, farnesyl-protein transferase beta-subunit, farnesyltransferase beta subunit, farnesyltransferase, CAAX box, beta, FNTB, FPTB, ft beta, FTase beta, FTase-beta, LOW QUALITY PROTEIN: protein farnesyltransferase subunit beta, protein farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2342, 64511
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins
- These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain
- CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine
- This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence
- The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.