mGluR5 Recombinant Rabbit Monoclonal Antibody (ST51-00), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532155-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532155 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
mGluR5
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P31424, P41594, Q3UVX5
Gene Symbols
Grm5
Immunogen
Synthetic peptide within Human GRM5 aa 1,163-1,212
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
ST51-00
Conjugate
Unconjugated
Gene
Grm5
Gene Alias
6430542K11Rik, A830007B11Rik, AI850523, D16Ium24, D16Ium24e, G protein coupled receptor, family C, group 1, member E, G protein-coupled receptor GRM5, G protein-coupled receptor, family C, group 1, member E, Glu5R, Glur5, Glur-5, Glurbeta1, glutamate metabotropic receptor 5, glutamate receptor, glutamate receptor, metabotropic 5, GPRC1A, GPRC1E, GRM 1, GRM 5, GRM1, GRM1 alpha, GRM1A, Grm5, metabotropic 1, metabotropic glutamate receptor (mGluR5), metabotropic glutamate receptor 5, metabotropic glutamate receptor 5b, metabotropic glutamate receptor subtype 5b, metabotropic glutamate receptor type 5, MGC25101, mGlu1, mGlu5, mGluR, mGluR1, mGluR1 alpha, mGluR1A, MGLUR5, mGluR5a, mGluR5b, PPP1R86, protein phosphatase 1, regulatory subunit 86
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
108071, 24418, 2915
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family
- GRK1 phosphorylates rhodopsin and initiates its deactivation
- G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain
- GRK1 is farnesylated to promote membrane association
- Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein
- Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.