GluR1 Recombinant Rabbit Monoclonal Antibody (SD2010), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532344-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532344 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
GluR1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P19490, P23818, P42261
Gene Symbols
GRIA1
Immunogen
Synthetic peptide within Human Glutamate receptor 1 aa 857-906
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
SD2010
Conjugate
Unconjugated
Gene
GRIA1
Gene Alias
2900051M01Rik, AI853806, AMPA 1, AMPA glutamate receptor, AMPA receptor GluR1/A, AMPA-selective glutamate receptor 1, Glr1, Glr-1, GluA1, GLUH 1, GLUH1, GluR K1, GLUR1, Glur-1, GluR1 flip, GluR1 flop, GLURA, GluR-A, GluRK1, gluR-K1, glutamate ionotropic receptor AMPA type subunit 1, glutamate receptor, glutamate receptor 1, glutamate receptor A, glutamate receptor ionotropic, AMPA 1, glutamate receptor subunit GluR1, glutamate receptor, ionotropic, AMPA 1, glutamate receptor, ionotropic, AMPA1 (alpha 1), GPRC1A, Gria 1, Gria1, GRM1A, HBGR1, HGBR1, HIPA, HIPA1, MGC13325, MGC133252, NMDA1, NMDAR1, NR1, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, RP11-350O14.1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14799, 2890, 50592
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor
- L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system
- Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse
- Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist
- In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.