POLB Recombinant Rabbit Monoclonal Antibody (JM93-12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532724-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532724 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
POLB
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P06746, P06766, Q6DRD3, Q8K409
Gene Symbols
POLB
Immunogen
Synthetic peptide within Human DNA Polymerase beta aa 286-335
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat, Zebrafish
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot
Clone
JM93-12
Conjugate
Unconjugated
Gene
POLB
Gene Alias
A430088C08Rik, DNA pol beta, DNA polymerase beta, DNA polymerase beta subunit, DNA-directed DNA polymerase beta, hypothetical protein LOC614688, LOW QUALITY PROTEIN: DNA polymerase beta, MGC125976, POL B, Pol beta, POLB, polb.S, polymerase (DNA directed), beta, polymerase (DNA directed), beta S homeolog, polymerase (DNA) beta, polymerase B, polymerase-beta, wu:fa97a05, XELAEV_18020165mg, zgc:109924
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18970, 29240, 5423, 554204
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- DNA polymerase beta comprises an amino-terminal 8- kDa domain and a carboxy-terminal 31- kDa domain
- The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity
- Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level
- DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.