P-Glycoprotein Recombinant Rabbit Monoclonal Antibody (SN06-42), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532282-Each-of-1 | In Stock | ₹ 53,934.00 |
PIMA532282 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,934.00
GST (18%): ₹ 9,708.12
Total Price: ₹ 63,642.12
Antigen
P-Glycoprotein
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P06795, P08183, P21447
Gene Symbols
ABCB1, Abcb1a, Abcb1b
Immunogen
Recombinant protein within Human P-glycoprotein 1 aa 373-730
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
SN06-42
Conjugate
Unconjugated
Gene
ABCB1
Gene Alias
ABC superfamily, P-glycoprotein, ABC20, ABCB1, Abcb1a, Abcb1b, Abcb4, ATP binding cassette subfamily B member 1, ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1), ATP-binding cassette sub-family B member 1, ATP-binding cassette sub-family B member 1A, ATP-binding cassette sub-family B member 1B, ATP-binding cassette transporter subfamily B, member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1), ATP-binding cassette, subfamily B (MDR/TAP), member 1A, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, ATP-binding cassette, subfamily B (MDR/TAP), member 1B, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, ATP-binding cassette, sub-family B (MDR/TAP), member 4, ATP-binding cassette, subfamily B, member 1A, ATP-binding cassette, subfamily B, member 1B, ATP-dependent translocase ABCB1, ATP-dependent translocase ABCB1, multidrug resistance protein 1, bovine p-glycoprotein, CD243, CLCS, colchicin sensitivity, doxorubicin resistance, ecotropic viral integration site 32, Evi32, GP170, mdr, Mdr1, MDR1A, Mdr1b, Mdr3, mdr-3, multi-drug resistance 3, multidrug resistance p-glycoprotein, multidrug resistance protein 1, Multidrug resistance protein 1A, multidrug resistance protein 1B, Multidrug resistance protein 2, multidrug resistance protein 3, multidrug resistance protein MDR1, multiple drug resistant 1a, P glycoprotein 1, P glycoprotein 3, P-glycoprotein, P-glycoprotein 1, P-glycoprotein 2, P-glycoprotein 3, P-glycoprotein/multidrug resistance 1, Pgp, p-gp, PGP1, PGP2, PGY1, Pgy-1, Pgy1-1, PGY2, Pgy3, Pgy-3, Phospholipid transporter ABCB1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
170913, 18669, 18671, 24646, 403879, 5243
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters
- ABC proteins transport various molecules across extra- and intra-cellular membranes
- ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)
- This protein is a member of the MDR/TAP subfamily
- Members of the MDR/TAP subfamily are involved in multidrug resistance
- The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity
- It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs
- This protein also functions as a transporter in the blood-brain barrier.