ABCA4 Monoclonal Antibody (3F4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533095-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA533095 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
ABCA4
Classification
Monoclonal
Concentration
∽1 mg/mL
Formulation
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5
Gene Accession No.
O35600, P78363
Gene Symbols
ABCA4, abca4.L
Immunogen
Partially purified bovine 220-kDa disc rim protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, X. laevis
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry, Western Blot
Clone
3F4
Conjugate
Unconjugated
Gene
ABCA4
Gene Alias
ABC transporter, ABC10, abca4, abca4.L, Abcr, ARMD2, ATP binding cassette subfamily A member 4, ATP binding cassette subfamily A member 4 L homeolog, ATP binding cassette transporter, ATP-binding cassette 10, ATP-binding cassette sub-family A member 4, ATP-binding cassette transporter, retinal-specific, ATP-binding cassette, subfamily A (ABC1), member 4, ATP-binding cassette, sub-family A (ABC1), member 4, ATP-binding cassette, sub-family A, member 4, ATP-binding transporter, retina-specific, AW050280, CORD3, D430003I15Rik, FFM, photoreceptor rim protein, retinal ABCA4 transporter, retinal-specific ATP-binding cassette transporter, Retinal-specific phospholipid-transporting ATPase ABCA4, retina-specific ABC transporter, RIM ABC transporter, RIM protein, RMP, RP19, Stargardt disease protein, STGD, STGD1, XELAEV_180233141mg
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
11304, 24, 281584, 497268
Content And Storage
-20°, C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Excitation: 405 nm; Emission: 645 nm; Laser: Blue Laser ABCA4 (ATP-Binding Cassette, Subfamily A, Member 4), also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene
- ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A (ABC1) found exclusively in multicellular eukaryotes
- Using a whole genome radiation hybrid panel, this gene is mapped to 1p21-p13
- And this gene is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane
- Additionally, it is showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone, as well as rod, photoreceptors
- The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration.