AGR2 Recombinant Rabbit Monoclonal Antibody (SN74-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532287-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532287 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
AGR2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O95994
Gene Symbols
Agr2
Immunogen
Synthetic peptide within Human AGR2 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SN74-01
Conjugate
Unconjugated
Gene
Agr2
Gene Alias
AG2, AG-2, AGR2, agr2 protein, Agr2h, AII, AII type II arginase, anterior gradient 2, anterior gradient 2 homolog, anterior gradient 2 homologue, anterior gradient 2, protein disulphide isomerase family member, anterior gradient homolog 2, anterior gradient protein 2 homolog, ARG2, arginase 2, arginase II, arginase type II, arginase, type II, arginase-2, mitochondrial, AU022422, epididymis secretory protein Li 116, Gob4, Gob-4, HAG-2, HEL-S-116, HPC8, kidney arginase, kidney-type arginase, L-arginine amidinohydrolase, L-arginine ureahydrolase, mAG-2, nonhepatic arginase, Non-hepatic arginase, PDIA17, protein disulfide isomerase family A, member 17, protein Gob-4, secreted cement gland homolog, secreted cement gland protein XAG-2 homolog, Type II arginase, UNQ515/PRO1030, XAG-2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10551
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family
- They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition
- They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours
- AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas
- AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).