Bcl-10 Recombinant Rabbit Monoclonal Antibody (SN74-04), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532327-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532327 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Bcl-10
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O95999
Gene Symbols
BCL10
Immunogen
Synthetic peptide within Human Bcl10 aa 198-233
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SN74-04
Conjugate
Unconjugated
Gene
BCL10
Gene Alias
AI132454, B cell CLL/lymphoma 10, B cell leukemia/lymphoma 10, B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, Bcl-10, BCL10 immune signaling adaptor, C81403, CARD containing molecule enhancing NF-kB, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, cE10, c-E10, CED-3/ICH-1 prodomain homologous E10-like regulator, cellular homolog of vCARMEN, Cellular-E10, CIPER, Clap, hCLAP, IMD37, Mamm, mammalian CARD-containing adapter molecule E10, mCIPER, mCLAP, mE10, OTTHUMP00000011647, OTTHUMP00000036080, RCD, RP11-234D19.2, R-RCD1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
8915
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response
- It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK
- BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex
- It is a substrate for MALT1
- Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.