Caspase 10 Recombinant Rabbit Monoclonal Antibody (JJ0890), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532459-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532459 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Caspase 10
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q92851
Gene Symbols
CASP10
Immunogen
Recombinant protein within Human Caspase-10 aa 254-452
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
JJ0890
Conjugate
Unconjugated
Gene
CASP10
Gene Alias
ALPS2, Apoptotic protease Mch-4, CASP10, CASP-10, caspase 10, caspase 10 apoptosis-related cysteine peptidase, caspase 10, apoptosis-related cysteine peptidase, caspase 10, apoptosis-related cysteine protease, caspase-10, Caspase-10 subunit p12, Caspase-10 subunit p23/17, FADD-like ICE2, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, interleukin-1B-converting enzyme 2, MCH4
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
843
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
- Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
- Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme
- This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8
- Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome
- Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.