PIMA532131

Calreticulin Recombinant Rabbit Monoclonal Antibody (SU37-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532131-Each-of-1 In Stock ₹ 49,083.50

PIMA532131 - Each of 1

₹ 49,083.50

In Stock

Quantity

1

Base Price: ₹ 49,083.50

GST (18%): ₹ 8,835.03

Total Price: ₹ 57,918.53

Antigen

Calreticulin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P14211, P18418, P27797

Gene Symbols

CALR

Immunogen

Synthetic peptide within Human Calreticulin aa 40-89

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot

Clone

SU37-03

Conjugate

Unconjugated

Gene

CALR

Gene Alias

Autoantigen RO, CABP3, CALBP, calcium-binding protein 3, CALR, calrectulin, calregulin, Calreticulin, calreticulin precursor, cC1qR, CRP55, CRT, CRTC, Endoplasmic reticulum resident protein 60, epididymis secretory sperm binding protein Li 99n, ERp60, FLJ26680, grp60, HACBP, HEL-S-99n, I79_008346, RO, Ro/SS-A Antigen, Sicca syndrome antigen A (autoantigen Ro, calreticulin), SSA

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12317, 64202, 811

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle
  • Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER
  • Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export
  • It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.