CDK5 Recombinant Rabbit Monoclonal Antibody (SR39-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531987-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA531987 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
CDK5
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P49615, Q00535, Q03114
Gene Symbols
CDK5
Immunogen
Synthetic peptide within Human Cdk5 aa 243-292
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
SR39-01
Conjugate
Unconjugated
Gene
CDK5
Gene Alias
AW048668, Cdk5, CDK5 activator 1, CDK5-SV, CDKN5, Cell division protein kinase 5, CR6 protein kinase, Crk6, cyclin dependent kinase 5, cyclin-dependent kinase 5, cyclin-dependent-like kinase 5, LIS7, protein kinase CDK5 splicing, PSSALRE, Serine/threonine-protein kinase PSSALRE, tau protein kinase II catalytic subunit, TPKII catalytic subunit
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1020, 12568, 140908
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain
- Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5
- CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system
- CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.