PIMA532373

RUNX1/RUNX2/RUNX3 Recombinant Rabbit Monoclonal Antibody (SD0803), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532373-Each-of-1 In Stock ₹ 46,413.50

PIMA532373 - Each of 1

₹ 46,413.50

In Stock

Quantity

1

Base Price: ₹ 46,413.50

GST (18%): ₹ 8,354.43

Total Price: ₹ 54,767.93

Antigen

RUNX1/RUNX2/RUNX3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q01196, Q03347, Q08775, Q13761, Q13950, Q63046, Q64131, Q9Z2J9

Gene Symbols

RUNX1, Runx2, RUNX3

Immunogen

Synthetic peptide within Human RUNX1 aa 404-453

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SD0803

Conjugate

Unconjugated

Gene

Runx2

Gene Alias

acute myeloid leukemia 1 protein, Acute myeloid leukemia 2 protein, acute myeloid leukemia 3 protein, acute myeloid leukemia gene 2, AKV core binding factor, AML1, AML1-EVI-1, AML1-EVI-1 fusion protein, AML2, Aml3, AMLCR1, Cbf, CBF2alpha, Cbfa1, Cbfa-1, CBFA2, Cbfa3, CBF-alpha-1, CBF-alpha-2, CBF-alpha-3, CCD, CCD1, CLCD, core binding factor alpha 1, core binding factor alpha 2, core binding factor alpha 3, core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene), core-binding factor subunit alpha-1, Core-binding factor subunit alpha-2, core-binding factor subunit alpha-3, core-binding factor, runt domain, alpha subunit 1, core-binding factor, runt domain, alpha subunit 2, core-binding factor, runt domain, alpha subunit 3, EVI-1, LS3, oncogene AML-1, Oncogene AML-2, oncogene AML-3, OSF2, OSF-2, Osteoblast-specific transcription factor 2, PEA2 alpha C, PEA2aA, PEA2-alpha A, PEA2-alpha B, PEA2-alpha C, PEBP2 alpha A, PEBP2 alpha C, Pebp2a, Pebp2a1, Pebp2a2, Pebp2a3, PEBP2aA, PEBP2aB, PEBP2aC, PEBP2alpha, PEBP2-alpha A, PEBP2-alpha B, PEBP2-alpha C, Pebpa2a, Pebpa2b, Polyomavirus enhancer-binding protein 2 alpha A subunit, polyomavirus enhancer-binding protein 2 alpha B subunit, Polyomavirus enhancer-binding protein 2 alpha C subunit, runt domain, alpha subunit 1, runt domain, alpha subunit 2, runt domain, alpha subunit 3, runt related transcription factor 1, runt related transcription factor 2, runt related transcription factor 3, runt-related transcription factor 1, Runt-related transcription factor 2, runt-related transcription factor 3, RUNX 2, Runx1, RUNX1/ZNF687 fusion, Runx2, RUNX-2, RUNX3, SL3/AKV core-binding factor alpha A subunit, SL3/AKV core-binding factor alpha B subunit, SL3/AKV core-binding factor alpha C subunit, SL3-3 enhancer factor 1 alpha A subunit, SL3-3 enhancer factor 1 alpha B subunit, SL3-3 enhancer factor 1 alpha C subunit, transcription factor, transcription factor AML2, transcription factor AML2/CBFA3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12393, 12394, 12399, 156726, 367218, 50662, 860, 861, 864

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters
  • The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis
  • Chromosomal translocations involving this gene are welldocumented and have been associated with several types of leukemia
  • Three transcript variants encoding different isoforms have been found for this gene.