TCF3 Recombinant Rabbit Monoclonal Antibody (SY0258), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532092-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532092 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
TCF3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P15923
Gene Symbols
TCF3
Immunogen
Synthetic peptide within Human TCF3 aa 71-120
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot
Clone
SY0258
Conjugate
Unconjugated
Gene
TCF3
Gene Alias
A1, AA408400, AGM8, Alf2, AW209082, bHLHb21, class B basic helix-loop-helix protein 21, E12, E12/E47, E2A, E47, helix-loop-helix protein HE47, immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, ITF1, Kappa-E2-binding factor, Me2, MGC129647, MGC129648, negative vitamin D response element-binding protein, NOL1-TCF3 fusion, Pan, Pan1, Pan2, pancreas specific transcription factor 1c, Ptf1c, TCF3, TCF-3, Tcfe2a, Transcription factor 3, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), transcription factor 3 variant 3, transcription factor A1, transcription factor E2a, Transcription factor E2-alpha, transcription factor ITF-1, Transcription regulator Pan, VDIR, VDR interacting repressor, vitamin D receptor-interacting repressor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6929
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation
- Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'
- Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer
- Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases
- Two alternatively spliced human isoforms have been described.