Cyclin A Recombinant Rabbit Monoclonal Antibody (SD2053), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532399-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532399 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Cyclin A
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P20248, P78396
Gene Symbols
CCNA1, CCNA2
Immunogen
Recombinant protein within Human Cyclin A1 + Cyclin A2 aa 253-440
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
SD2053
Conjugate
Unconjugated
Gene
CCNA2
Gene Alias
AA408589, CCN1, Ccn-1, CCNA, Ccna1, CCNA2, CT146, Cyca, Cyca2, Cyclin A, cyclin A1, cyclin A2, Cyclin A2 (Cyclin A), CyclinA, cyclin-A, CyclinA1, Cyclin-A1, cyclin-A2, testicular tissue protein Li 34
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
890, 8900
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established
- The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor
- Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2)
- In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110
- A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells
- It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.