PIMA532331

Cyclin H Recombinant Rabbit Monoclonal Antibody (SN20-48), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532331-Each-of-1 In Stock ₹ 47,481.50

PIMA532331 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Cyclin H

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P51946, Q61458

Gene Symbols

CCNH

Immunogen

Recombinant protein within Human Cyclin H aa 230-323

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SN20-48

Conjugate

Unconjugated

Gene

CCNH

Gene Alias

6330408H09Rik, AI661354, AV102684, AW538719, CAK, CAK complex subunit, Ccnh, CDK-activating kinase complex subunit, CycH, cyclin H, cyclin-dependent kinase-activating kinase complex subunit, cyclin-H, MO15-associated protein, OTTHUMP00000222395, OTTHUMP00000222396, p34, p37

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

66671, 902

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
  • Cyclins function as regulators of CDK kinases
  • Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
  • This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1
  • The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK)
  • This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes
  • They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.