VAMP2 Recombinant Rabbit Monoclonal Antibody (JM11-00), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532606-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532606 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
VAMP2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P63027, P63044, P63045
Gene Symbols
VAMP2
Immunogen
Synthetic peptide within Human VAMP2 aa 9-42
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone
JM11-00
Conjugate
Unconjugated
Gene
VAMP2
Gene Alias
RATVAMPB, RATVAMPIR, SYB, SYB2, Syb-2, sybII, Synaptobrevin, synaptobrevin 2, Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2), synaptobrevin II, synaptobrevin-2, vamp, Vamp2, VAMP-2, vesicle associated membrane protein 2, vesicle-associated membrane 2, Vesicle-associated membrane protein (synaptobrevin 2), vesicle-associated membrane protein 2, vesicle-associated membrane protein 2 (synaptobrevin 2)
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
22318, 24803, 6844
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes
- VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP
- These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane
- The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP
- In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered
- It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.