PIMA532608
CD104 (Integrin beta 4) Recombinant Rabbit Monoclonal Antibody (JM11-06), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532608-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532608 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
CD104 (Integrin beta 4)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
A2A863, P16144
Gene Symbols
ITGB4
Immunogen
Recombinant protein within mouse Integrin beta 4 aa 1564-1822
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JM11-06
Conjugate
Unconjugated
Gene
ITGB4
Gene Alias
AA407042, C230078O20, CD antigen CD104, CD104, CD104 antigen, GP150, integrin beta 4, integrin beta-4, integrin subunit beta 4, integrin, beta 4, Itgb4
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
192897, 3691
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors
- Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities
- Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth
- This gene encodes the integrin beta 4 subunit, a receptor for the laminins
- This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma
- Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia
- Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.