MYOD Recombinant Rabbit Monoclonal Antibody (JM10-72), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532641-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532641 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
MYOD
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P15172
Gene Symbols
MYOD1
Immunogen
Synthetic peptide within Human MyoD1 aa 36-80
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
JM10-72
Conjugate
Unconjugated
Gene
MYOD1
Gene Alias
AI503393, bHLHc1, Class C basic helix-loop-helix protein 1, CMD1, MYF3, Myf-3, Myoblast determination protein 1, myoblast determination protein 1 homolog, Myod, MYOD1, Myod-1, MYOD1 homolog, myogenic differentiation 1, myogenic factor 1, myogenic factor 3, PUM, unnamed protein product
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4654
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells
- It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells
- The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif
- Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD
- These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).