GCN2 Recombinant Rabbit Monoclonal Antibody (JA03-83), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532704-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532704 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
GCN2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q9P2K8
Gene Symbols
EIF2AK4
Immunogen
Synthetic peptide within Human GCN2 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JA03-83
Conjugate
Unconjugated
Gene
EIF2AK4
Gene Alias
2610011M03, EIF2AK4, eIF-2-alpha kinase GCN2, eukaryotic translation initiation factor 2 alpha kinase 4, eukaryotic translation initiation factor 2-alpha kinase 4, Gcn2, GCN2 eIF2alpha kinase, GCN2-like protein, general control nonderepressible 2, Kiaa1338, mGCN2, PVOD2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
440275
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability
- It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation
- Mutations in the gene lead to pulmonary vennocclusive disease 2.