Alpha Sarcoglycan Recombinant Rabbit Monoclonal Antibody (JA51-81), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532672-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532672 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Alpha Sarcoglycan
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P82350, Q16586
Gene Symbols
SGCA
Immunogen
Synthetic peptide within Human alpha sarcoglycan aa 338-387
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
JA51-81
Conjugate
Unconjugated
Gene
SGCA
Gene Alias
50 kDa dystrophin-associated glycoprotein, 50DAG, 50kD DAG, adhalin, ADL, Alpha-sarcoglycan, alpha-SG, Asg, DAG2, DMDA2, Dystroglycan 2, Dystroglycan2, dystroglycan-2, LGMD2D, limb girdle muscular dystrophy 2D, sarcoglycan alpha, sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein), sarcoglycan, alpha (dystrophin-associated glycoprotein), SCARMD1, SG alpha, SG-alpha, Sgca
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20391, 303468, 6442
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The sarcoglycan transmembrane proteins are members of the dystrophin complex
- Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers
- Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane
- A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy
- In smooth muscle, beta- and delta-sarcoglycans are associated with epsilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan
- Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.