alpha Internexin Recombinant Rabbit Monoclonal Antibody (JU25-03), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532809-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532809 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
alpha Internexin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P23565, P46660, Q16352
Gene Symbols
INA
Immunogen
Synthetic peptide within Human alpha Internexin aa 394-443
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JU25-03
Conjugate
Unconjugated
Gene
INA
Gene Alias
66 kDa neurofilament protein, Alpha-internexin, alpha-Inx, AV028420, FLJ18662, FLJ57501, Ina, Inexa, internexin neuronal intermediate filament protein alpha, internexin neuronal intermediate filament protein, alpha, internexin, alpha, Intlaa, LOW QUALITY PROTEIN: alpha-internexin, MGC12702, NEF5, Neuro, Neurofilament 5, neurofilament 5 (66kD), Neurofilament 66, neurofilament-66, neurofilament-66, tax-binding protein, Nf66, NF-66, TXBP-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
226180, 24503, 9118
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development
- It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization
- Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H
- In some mature neurons a-internexin is the only neurofilament subunit expressed
- Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture
- In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage
- The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest.