ATG3 Recombinant Rabbit Monoclonal Antibody (JU00-35), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532815-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532815 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
ATG3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q6AZ50, Q9CPX6, Q9NT62
Gene Symbols
ATG3
Immunogen
Synthetic peptide within Human Apg3 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
JU00-35
Conjugate
Unconjugated
Gene
ATG3
Gene Alias
2610016C12Rik, APG3, Apg3l, APG3-like, Apg3p, atg3, ATG3 autophagy related 3 homolog, atg3.S, Atg3l, autophagy related 3, autophagy related 3 S homeolog, autophagy-related 3, autophagy-related protein 3, DKFZp564M1178, EGK_11288, FLJ22125, hApg3, MGC15201, PC3-96, Pig1, PIG-1, preconditioning-inducible gene 1 protein, Protein PC3-96, Ubiquitin-like-conjugating enzyme ATG3, XELAEV_18014721mg
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
171415, 64422, 67841
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
- Autophagy is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
- This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1
- ATG3 functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.