ATG12 Monoclonal Antibody (1-11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532923-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532923 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
ATG12
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O94817, Q2TBJ5, Q9CQY1
Gene Symbols
ATG12
Immunogen
Synthetic peptide within Human Atg12 aa 91-140.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgE
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
1-11
Conjugate
Unconjugated
Gene
ATG12
Gene Alias
4931423H11Rik, A330058M13Rik, APG 12, APG12, Apg12 (autophagy, yeast) homolog, APG12L, APG12-like, ATG12, ATG12 autophagy related 12 homolog, Atg12l, Atg12p, Atg12-PB, Autophagy protein 12-like, autophagy related 12, autophagy related protein 12, autophagy-related 12, autophagy-related protein 12, Autophagy-specific gene 12, CG10861, CG10861-PB, Dmel\CG10861, Dmel_CG10861, FBR93, HAPG12, IP05205p, IP05405p, OTTHUMP00000159129, ubiquitin-like protein ATG12, YBR1506, YBR217W
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
361321, 67526, 9140
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Mouse Monoclonal Antibody ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy
- This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
- ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7
- At least two isoforms of ATG12 are known to exist
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
- It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
- This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.