TGM2 Recombinant Rabbit Monoclonal Antibody (JU30-02), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532819-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532819 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
TGM2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P21980, P21981
Gene Symbols
TGM2
Immunogen
Synthetic peptide within Human Transglutaminase 2 aa 578-627
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
JU30-02
Conjugate
Unconjugated
Gene
TGM2
Gene Alias
C polypeptide, C polypeptide, protein-glutamine-gamma-glutamyltransferase, G alpha h, G[a]h, G-ALPHA-h, GNAH, Protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, RP5-1054A22.2, TG C, TG(C), TG2, TGase C, TGase H, TGase2, TGase-2, TGase-H, TgaseII, TGC, TGM2, Tissue transglutaminase, Tissue type transglutaminase, tissue-type transglutaminase, transglutaminase, transglutaminase 2, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase 2 C polypeptide, transglutaminase 2, C polypeptide, transglutaminase C, Transglutaminase H, transglutaminase-2, tTG, tTGas
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
21817, 7052
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Transglutaminase (TGase) catalyses the crosslink of proteins by forming e-(g-glutamyl) lysine isopeptide bonds and requires the binding of Ca2+ for its activity
- In mammals, eight distinct TGase isoenzymes have been identified
- Tissue transglutaminase (tTGase), also known as TGase 2, has four distinct domains: N-terminal b-sandwich, catalytic core and two C-terminal b-barrel domains
- tTGase may have a role in cell death, cell proliferation, cell differentiation, and receptor-mediated endocytosis
- In the Alzheimer's disease brain, the elevated tTGase activity is manifested by polymerization of a number of proteins, including Ab peptide, b-amyloid precursor protein and the tau protein, with formation of neurofibrillary tangles.