PIMA532591

GBA Recombinant Rabbit Monoclonal Antibody (JM10-76), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532591-Each-of-1 In Stock ₹ 47,481.50

PIMA532591 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

GBA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P04062

Gene Symbols

GBA

Immunogen

Synthetic peptide within Human GBA aa 477-534

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Clone

JM10-76

Conjugate

Unconjugated

Gene

GBA

Gene Alias

acid beta glucosidase, acid beta-glucosidase, Alglucerase, betaGC, beta-GC, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, Cholesteryl-beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Gba, GBA1, GBAP, GBAP1, GC, GCase, GCB, GLUC, glucocerebrosidase, glucosidase, beta, acid, glucosylceramidase, glucosylceramidase beta, glucosylceramidase beta pseudogene 1, glucosylceramidase-like protein, imiglucerase, Lysosomal acid GCase, Lysosomal acid glucosylceramidase, lysosomal glucocerebrosidase, SGTase

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2629, 684536

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism
  • Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides
  • A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1
  • Alternative splicing results in multiple transcript variants.