TIM-3 Monoclonal Antibody (1E6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532839-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532839 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
TIM-3
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q8TDQ0
Gene Symbols
Havcr2
Immunogen
Recombinant protein with Human Tim3 1-89
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
1E6
Conjugate
Unconjugated
Gene
Havcr2
Gene Alias
CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
84868
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Mouse Monoclonal Antibody TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells
- TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region
- TIM3 is involved in macrophage activation and induction of autoimmune diseases
- Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance
- Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 dependent autoimmune disease, and also enhances the severity of experimental autoimmune encephalomyelitis in mice.