GCLC Recombinant Rabbit Monoclonal Antibody (JA08-03), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532850-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532850 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
GCLC
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P19468, P48506
Gene Symbols
Gclc
Immunogen
Synthetic peptide within Human GCLC aa 588-637
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
JA08-03
Conjugate
Unconjugated
Gene
Gclc
Gene Alias
cb1049, D9Wsu168e, EGK_15023, fe36e11, gamma GCS-HS, gamma-ECS, Gamma-glutamylcysteine synthetase, gamma-glutamylcysteine synthetase heavy subunit, GCL, Gclc, GCS, GCS heavy chain, Ggcs-hs, GLCL, GLCLC, GLCL-H, glutamate-cysteine ligase catalytic subunit, Glutamate--cysteine ligase catalytic subunit, glutamate-cysteine ligase, catalytic subunit, Glutamylcysteine gamma synthetase light chain, wu:fe36e11
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
25283, 2729
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis
- The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit
- This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21
- Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.