GCLC Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103134-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103134 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GCLC
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Gclc
Gene Alias
cb1049; D9Wsu168e; EGK_15023; fe36e11; gamma GCS-HS; gamma-ECS; Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase heavy subunit; GCL; Gclc; GCS; GCS heavy chain; Ggcs-hs; GLCL; GLCLC; GLCL-H; glutamate-cysteine ligase catalytic subunit; Glutamate--cysteine ligase catalytic subunit; glutamate-cysteine ligase, catalytic subunit; Glutamylcysteine gamma synthetase light chain; wu:fe36e11
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100522018, 14629, 25283, 2729
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P19468, P48506, P97494
Gene Symbols
Gclc
Immunogen
A synthesized peptide derived from human GCLC(Accession P48506), corresponding to amino acid residues K73-N123.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total GCLC
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis
- The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit
- This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21
- Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.