AMPK beta-2 Monoclonal Antibody (6G1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533002-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533002 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
AMPK beta-2
Classification
Monoclonal
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
O43741
Gene Symbols
Prkab2
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 2 (56-89aa DKEFVSWQQDLEDSVKPTQQARPTVIRWSEGGKE).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
6G1
Conjugate
Unconjugated
Gene
Prkab2
Gene Alias
5730553K21Rik, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase, beta-2 subunit, AMP-activated protein kinase beta 2 non-catalytic subunit, AMP-activated protein kinase beta-2 regulatory subunit, AMPK beta 2, AMPK beta-2 chain, AMPK subunit beta-2, AMPKbeta2, AW049591, BB124140, Prkab2, protein kinase AMP-activated non-catalytic subunit beta 2, protein kinase, AMP-activated, beta 2 non-catalytic subunit
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5565
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
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Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK)
- AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
- AMPK is an important energy-sensing enzyme that monitors cellular energy status
- In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
- This subunit may be a positive regulator of AMPK activity
- The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK
- This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.