AMPK beta-1 Monoclonal Antibody (1A7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532975-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA532975 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
AMPK beta-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P80386, Q9R078, Q9Y478
Gene Symbols
PRKAB1
Immunogen
Purified recombinant human AMPKbeta1 protein fragments expressed in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Clone
1A7
Conjugate
Unconjugated
Gene
PRKAB1
Gene Alias
1300015D22Rik, 5'-AMP-activated protein kinase 40 kDa subunit, 5-AMP-activated protein kinase beta subunit, 5'-AMP-activated protein kinase beta-1 subunit, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-1-like protein, 5'-AMP-activated protein kinase, beta subunit, AAKB1, AMP-activated protein kinase beta subunit, AMPK, AMPK beta 1, AMPK beta -1 chain, AMPK beta-1 chain, AMPK subunit beta-1, AMPKb, AMPK-beta1, AU021155, E430008F22, HAMPKb, kinase AMPK-beta1, kinase pAMPK, pAMPK, Prkab1, protein kinase AMP-activated non-catalytic subunit beta 1, protein kinase, AMP-activated, beta 1 non-catalytic subunit, protein kinase, AMP-activated, noncatalytic, beta-1
Host Species
Mouse
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19079, 5564, 83803
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK)
- AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
- AMPK is an important energy-sensing enzyme that monitors cellular energy status
- In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
- This subunit may be a positive regulator of AMPK activity
- The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK
- This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.