Phospho-AMPK alpha-2 (Thr172) Recombinant Rabbit Monoclonal Antibody (4F4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533216-Each-of-1 | In Stock | ₹ 51,842.50 |
PIMA533216 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,842.50
GST (18%): ₹ 9,331.65
Total Price: ₹ 61,174.15
Antigen
Phospho-AMPK alpha-2 (Thr172)
Classification
Recombinant Monoclonal
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P54646
Gene Symbols
PRKAA2
Immunogen
A synthesized peptide derived from human Phospho-PRKAA2 (Thr172)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
4F4
Conjugate
Unconjugated
Gene
PRKAA2
Gene Alias
2310008I11Rik, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase, catalytic alpha-2 chain, A830082D05, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP-activated protein kinase, AMP-activated protein kinase alpha-2 subunit variant 2, AMP-activated protein kinase alpha-2 subunit variant 3, AMP-activated protein kinase alpha-2 variant B, AMPK, AMPK alpha 2, AMPK alpha-2 chain, AMPK subunit alpha-2, AMPK2, AMPKa2, AMPKalpha2, AMPK-alpha-2 chain, EC 2.7.11.1, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, PRKAA, Prkaa2, protein kinase AMP-activated catalytic subunit alpha 2, protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5563
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK)
- AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
- AMPK is an important energy-sensing enzyme that monitors cellular energy status
- In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
- Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.