PIMA533004

GSTM1 Monoclonal Antibody (11F2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533004-Each-of-1 In Stock ₹ 47,481.50

PIMA533004 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

GSTM1

Classification

Monoclonal

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

P04905, P09488, P10649

Gene Symbols

GSTM1

Immunogen

A synthetic peptide corresponding to a sequence of human GSTM1 (EEEKIRVDIL ENQTMDNHMQLGMICYNPEFEKLK).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

11F2

Conjugate

Unconjugated

Gene

GSTM1

Gene Alias

glutathione S-alkyltransferase, glutathione S-aralkyltransferase, glutathione S-aryltransferase, glutathione S-transferase GT8.7, glutathione S-transferase M1, glutathione S-transferase Mu 1, Glutathione S-transferase Yb-1, glutathione S-transferase Yb-1 subunit, glutathione S-transferase, mu 1, glutathione-S-transferase mu type 1 (Yb1), glutathione-S-transferase, mu 1, glutathione-S-transferase, mu type 1 (Yb1), GST 1-1, GST 3-3, GST class-mu 1, GST HB subunit 4, GST Yb1, GST1, GSTA3, Gstb1, Gstb-1, GSTM1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, HB subunit 4, MU, MU-1, pmGT10, S-(hydroxyalkyl)glutathione lyase

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14862, 24423, 2944

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families
  • At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta
  • This gene encodes a glutathione S-transferase that belongs to the mu class
  • The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
  • The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13
  • 3 and are known to be highly polymorphic
  • These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs
  • Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens
  • Multiple protein isoforms are encoded by transcript variants of this gene.