PIMA533088
IRF4 Recombinant Rabbit Monoclonal Antibody (RM352), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533088-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533088 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
IRF4
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
Q15306
Gene Symbols
IRF4
Immunogen
A peptide corresponding to the C-terminus of human MUM1/IRF4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM352
Conjugate
Unconjugated
Gene
IRF4
Gene Alias
AI385587, interferon regulatory factor 4, Irf4, IRF-4, LSIRF, Lymphocyte-specific interferon regulatory factor, multiple myeloma oncogene 1, MUM1, NF-EM5, PU.1 interaction partner, Sfpi1/PU.1 interaction partner, SHEP8, Spip, Transcriptional activator PIP
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3662
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human MUM1/IRF4 (Multiple myeloma oncogene 1) (Interferon regulatory factor 4)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain
- The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes
- IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems
- A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma
- Alternatively spliced transcript variants have been found.