PAX5 Recombinant Rabbit Monoclonal Antibody (RM331), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533084-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533084 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
PAX5
Classification
Recombinant Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
Q02548
Gene Symbols
PAX5
Immunogen
A peptide corresponding to C-terminus of human Paired box protein Pax-5.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM331
Conjugate
Unconjugated
Gene
PAX5
Gene Alias
ALL3, B-cell lineage specific activator, B-cell-specific transcription factor, BSAP, EBB-1, KLP, paired box 5, paired box gene 5, paired box gene 5 (B-cell lineage specific activator), paired box homeotic gene 5, paired box protein Pax-5, paired domain gene 5, Pax5, Pax-5, Pax5 variant 1, Pax5 variant 2, RGD1565236, transcription factor PAX 5
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5079
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human Paired box protein Pax-5
- It may also react to mouse Paired box protein Pax-5, as predicted by immunogen homology
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- PAX5 is a member of the paired box (PAX) family of transcription factors
- The PAX proteins are important regulators in early development and alterations in the expression of their genes are thought to contribute to neoplastic transformation
- PAX5 is the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages, of B-cell differentiation
- Its expression has also been detected in developing CNS and testis, therefore, PAX5 may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis
- Mutations in the gene can result in leukemia, acute lymphoblastic 3.