PIMA533034
NAPSA Recombinant Rabbit Monoclonal Antibody (RM366), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533034-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533034 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
NAPSA
Classification
Recombinant Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
O96009
Gene Symbols
NAPSA
Immunogen
A peptide corresponding to the N-terminus of human Napsin-A.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM366
Conjugate
Unconjugated
Gene
NAPSA
Gene Alias
asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, KDAP-1, kidney-derived aspartic protease-like protein, Nap, NAP1, NAPA, Napsa, napsin A aspartic peptidase, napsin-1, Napsin-A, pronapsin, pronapsin A, SNAPA, TA01/TA02
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
9476
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts human Napsin-A
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body
- Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs
- Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases
- When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types
- Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.