TSPO Recombinant Rabbit Monoclonal Antibody (23G2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533203-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA533203 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
TSPO
Classification
Recombinant Monoclonal
Concentration
0.94 mg/mL
Formulation
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P30536, P50637
Gene Symbols
Tspo
Immunogen
A synthesized peptide derived from human TSPO (50-169aa)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone
23G2
Conjugate
Unconjugated
Gene
Tspo
Gene Alias
Benzodiazepin receptor (peripheral), benzodiazepine peripheral binding site, benzodiazepine receptor, peripheral, BPBS, BZRP, DBI, IBP, isoquinoline-binding protein, MBR, mDRC, mitochondrial benzodiazepine receptor, OTTHUMP00000028891, PBR, PBS, peripheral-type benzodiazepine receptor, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, translocator protein, translocator protein (18kDa), TSPO, Tspo1
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
12257, 706
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- Mitochondrial peripheral-type benzodiazepine receptor (PBR) is an indispensable element of the steroidogenic machinery, where it mediates the delivery of cholesterol to the inner mitochondrial side chain cleavage cytochrome P-450 upon ligand activation
- PBR is composed of three subunits, an isoquinoline binding site, a voltage-dependent anion channel and an adenine nucleotide carrier
- PBR is genetically conserved from bacteria to humans and in humans is widely expressed in peripheral organs, whereas in the brain, it is sparse and located mainly in glial cells
- Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation
- A cytoplasmic protein, PRAX-1 ( peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.