GTPBP4 Recombinant Rabbit Monoclonal Antibody (JE47-47), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534853-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
GTPBP4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q9BZE4
Gene Symbols
Gtpbp4
Immunogen
Recombinant protein within Human GTPBP4 aa 1-131
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE47-47
Conjugate
Unconjugated
Gene
Gtpbp4
Gene Alias
2610028C09Rik; chronic renal failure gene protein; chronic renal failure protein; Crfg; fi28d07; FLJ10686; FLJ10690; FLJ39774; G protein-binding protein CRFG; GTP binding protein 3; GTP binding protein 4; GTP binding protein NGB; GTP-binding protein NGB; Gtpbp3; Gtpbp4; NGB; Nog1; nucleolar GTP-binding protein 1; Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB); Unknown (protein for IMAGE:7956347); wu:fi28d07; zgc:55757
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23560
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: 293T cell, human liver cancer tissue, human thyroid gland tissue, human skin tissue, human breast tissue, thp-1
- GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound
- 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell
- When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP
- The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP
- But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.