PIMA534860
HSF2 Recombinant Rabbit Monoclonal Antibody (JE48-40), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534860-Each-of-1 | In Stock | ₹ 47,036.50 |
PIMA534860 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
HSF2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q03933
Gene Symbols
HSF2
Immunogen
Recombinant protein within Human HSF2 aa 426-536
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE48-40
Conjugate
Unconjugated
Gene
HSF2
Gene Alias
AI661205; heat shock factor 2; heat shock factor protein 2; Heat shock transcription factor 2; HSF 2; Hsf2; HSTF 2; HSTF2; MGC117376; MGC156196; MGC75048
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3298
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: Daudi, HepG2, human breast cancer tissue, human prostate cancer tissue, human skin tissue, human colon cancer tissue, human gastric cancer tissue, 293
- Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes
- In eukaryotes, this gene expression is regulated primarily at the transcription level
- Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation
- HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level
- HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation
- Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus
- HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer
- Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.