E2F1 Recombinant Rabbit Monoclonal Antibody (ARC0058), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535306-Each-of-1 | In Stock | ₹ 46,947.50 |
PIMA535306 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,947.50
GST (18%): ₹ 8,450.55
Total Price: ₹ 55,398.05
Antigen
E2F1
Classification
Monoclonal
Concentration
0.4 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O09139, Q01094, Q61501
Gene Symbols
E2F1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 338-437 of human E2F1 (Q01094)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Clone
ARC0058
Conjugate
Unconjugated
Gene
E2F1
Gene Alias
E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13555, 1869, 399489
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: PPSSLTTDPS QSLLSLEQEP LLSRMGSLRA PVDEDRLSPL VAADSLLEHV REDFSGLLPE EFISLSPPHE ALDYHFGLEE GEGIRDLFDC DFGDLTPLDF The protein encoded by this gene is a member of the E2F family of transcription factors
- The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
- The E2F proteins contain several evolutionally conserved domains found in most members of the family
- These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
- This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain
- This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner
- It can mediate both cell proliferation and p53-dependent/independent apoptosis.