PIMA535875

Phospho-PRKAR2A (Ser99) Recombinant Rabbit Monoclonal Antibody (ARC1579), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535875-Each-of-1 In Stock ₹ 50,507.50

PIMA535875 - Each of 1

₹ 50,507.50

In Stock

Quantity

1

Base Price: ₹ 50,507.50

GST (18%): ₹ 9,091.35

Total Price: ₹ 59,598.85

Antigen

Phospho-PRKAR2A (Ser99)

Classification

Monoclonal

Concentration

0.95 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P12368, P13861

Gene Symbols

PRKAR2A

Immunogen

A synthetic phosphorylated peptide around S99 of human PRKAR2A/PKR2 (P13861)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC1579

Conjugate

Unconjugated

Gene

PRKAR2A

Gene Alias

1110061A24Rik; AI317181; AI836829; cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; cAMP-dependent protein kinase, regulatory subunit alpha 2; MGC3606; PKR2; PRKAR2; Prkar2a; protein kinase A, RII-alpha subunit; protein kinase cAMP-dependent regulatory type II alpha; protein kinase cAMP-dependent type II regulatory subunit alpha; protein kinase, cAMP dependent regulatory, type II alpha; protein kinase, cAMP-dependent, regulatory subunit type II alpha; protein kinase, cAMP-dependent, regulatory, type 2, alpha; protein kinase, cAMP-dependent, regulatory, type II, alpha; RII(alpha); unnamed protein product

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29699, 5576

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: RVSVC cAMP is a signaling molecule important for a variety of cellular functions
  • cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins
  • The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits
  • cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
  • Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans
  • The protein encoded by this gene is one of the regulatory subunits
  • This subunit can be phosphorylated by the activated catalytic subunit
  • It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.