GBL Monoclonal Antibody (211CT7.1.1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537512-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA537512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
GBL
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.09% sodium azide
Gene Accession No.
Q9DCJ1
Gene Symbols
MLST8
Immunogen
GBL recombinant protein
Regulatory Status
RUO
Gene ID (Entrez)
56716
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Clone
211CT7.1.1
Conjugate
Unconjugated
Gene
MLST8
Gene Alias
0610033N12Rik; AA409454; AI505104; AI851821; G beta-like protein; G protein beta subunit-like; Gable; GbetaL; GBL; GBL protein; Lst8; Mammalian lethal with SEC13 protein 8; mLST8; mLST8 / mLST8; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); POP3; protein GbetaL; Target of rapamycin complex subunit LST8; TORC subunit gable; TORC subunit LST8; TORC subunit WAT1; transducin (beta)-like 4; WAT1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- G-protein beta subunit like (GBL protein) is a novel member of WD-40 protein family
- It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs
- LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway
- It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor
- LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1
- Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis
- Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis.