PIMA542347
Zika Virus NS1 Monoclonal Antibody (GT5212), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542347-Each-of-1 | In Stock | ₹ 45,790.50 |
PIMA542347 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,790.50
GST (18%): ₹ 8,242.29
Total Price: ₹ 54,032.79
Antigen
Zika Virus NS1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and no preservative; pH 7
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
GT5212
Conjugate
Unconjugated
Gene Alias
Zika NS1; ZIKV NS1; ZIKV-NS1
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Zika virus NS1 protein (Zika virus (strain H/PF/2013). The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- For short-term storage (1-2 weeks), store at 4°C
- For long-term storage, aliquot and store at -20°C or below
- Avoid multiple freeze-thaw cycles
- As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1)
- The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2)
- NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1)
- Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F
- (2016)
- Nat
- Struct
- Mol
- Biol
- 23, 456-458
- 2) Suthar, M.S., Diamond, M.S
- & Gale, M
- Jr
- (2013)
- Nat
- Rev
- Microbiol
- 11, 115-128.