PTBP1 Monoclonal Antibody (5C1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544599-Each-of-1 | In Stock | ₹ 42,720.00 |
PIMA544599 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,720.00
GST (18%): ₹ 7,689.60
Total Price: ₹ 50,409.60
Antigen
PTBP1
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P26599, Q00438
Gene Symbols
PTBP1
Immunogen
Synthetic peptide within Human PTBP1 aa 1-50/531.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
5C1
Conjugate
Unconjugated
Gene
PTBP1
Gene Alias
57 kDa RNA-binding protein PPTB-1; AA407203; AL033359; Heterogeneous nuclear ribonucleoprotein I; heterogeneous nuclear ribonucleoprotein polypeptide I; hnRNP I; HNRNPI; HNRNP-I; HNRPI; MGC10830; MGC8461; polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I); polypyrimidine tract binding protein 1; polypyrimidine tract-binding protein; polypyrimidine tract-binding protein 1; polypyrimidine-tract binding protein; pPTB; PTB; PTB-1; PTB2; PTB3; PTB4; PTBP1; PTB-T; Pybp; Pybp1; Pybp2; pyrimidine binding protein 1; pyrimidine binding protein 2; RNA-binding protein
Host Species
Mouse
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29497, 5725
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)
- The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA)
- These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport
- While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm
- The hnRNP proteins have distinct nucleic acid binding properties
- The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs
- This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway
- It may also promote the binding of U2 snRNP to pre-mRNAs
- This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure
- Alternatively spliced transcript variants encoding different isoforms have been described.