PIMA547295

ENO1 Monoclonal Antibody (253), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547295-Each-of-1 In Stock ₹ 1,49,520.00

PIMA547295 - Each of 1

₹ 1,49,520.00

In Stock

Quantity

1

Base Price: ₹ 1,49,520.00

GST (18%): ₹ 26,913.60

Total Price: ₹ 1,76,433.60

Antigen

ENO1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.

P04764, P06733, P17182, Q9XSJ4

Gene Symbols

ENO1

Immunogen

N-terminal 12 amino acids of bovine enolase 1

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Bovine, Equine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

253

Conjugate

Unconjugated

Gene

ENO1

Gene Alias

0610008I15; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydro-lyase; AL022784; alpha enolase; alpha enolase like 1; alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; c-Myc promoter binding protein; C-myc promoter-binding protein; Eno1; Eno-1; ENO1L1; enoa; Enolase 1; enolase 1, (alpha); enolase 1, alpha non-neuron; enolase-alpha; epididymis secretory protein Li 17; HEL-S-17; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

100051879, 100738870, 13806, 2023, 24333, 281141

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Enolase (2-phosphogly-cerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the dehydration and conversion of 2-phosphoglycerate to phosphoenolpyruvate
  • It comprises three distinct subunits, alpha, beta and gamma
  • Non Neuronal Enolase(ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits
  • The gene for ENO1 also encodes a shorter monomeric structural lens protein, tau-crystallin
  • Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses
  • May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons
  • Stimulates immunoglobulin production.Used as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest
  • Also marker for endometriosis
  • Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies
  • Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT)
  • HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.