PIPA596148

GNAO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596148-Each-of-1 In Stock ₹ 46,502.50

PIPA596148 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

GNAO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GNAO1

Gene Alias

alphaO, AW050213, DKFZp686O0962, EIEE17, G alpha o, G protein subunit alpha o1, Galphao, G-ALPHA-o, Gna0, Gnao, GNAO 1, Gnao1, Go alpha, GO2-q chimeric G-protein, GTP-binding protein alpha o, GTP-binding protein alpha-o subunit, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, guanine nucleotide binding protein, alpha O, guanine nucleotide binding protein, alpha O polypeptide 1, guanine nucleotide-binding protein G(o) subunit alpha, guanine nucleotide-binding regulatory protein 2, HLA-DQB1, RATBPGTPC

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14681, 2775, 50664

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.63 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P09471, P18872, P59215

Gene Symbols

GNAO1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human GNAO1 (NP_0662681)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GFSGEDVKQY KPVVYSNTIQ SLAAIVRAMD TLGIEYGDKE RKADAKMVCD VVSRMEDTEP FSAELLSAMM RLWGDSGIQE CFNRSREYQL NDSAKYYLDS LDRIGAADYQ PTEQDILRTR V; Positive Samples: Mouse brain, Mouse spinal cord; Cellular Location: Cell membrane, Lipid-anchor, Membrane Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors
  • Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state
  • Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades
  • There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.