MECP2 Monoclonal Antibody (5H12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547451-Each-of-1 | In Stock | ₹ 43,654.50 |
PIMA547451 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,654.50
GST (18%): ₹ 7,857.81
Total Price: ₹ 51,512.31
Antigen
MECP2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
P51608, Q00566, Q9Z2D6
Gene Symbols
Mecp2
Immunogen
Recombinant full length human MeCP2 expressed in and purified from E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Clone
5H12
Conjugate
Unconjugated
Gene
Mecp2
Gene Alias
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
17257, 29386, 4204
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
- MECP2 is capable of binding specifically to methylated DNA
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
- MECP2 can also repress transcription from methylated gene promoters
- In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
- MECP2 is dispensible in stem cells, but is essential for embryonic development
- MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.